Acute kidney injury. Acute renal failure
Conditions
Interventions
Intervention 1: Intervention group: Erythropoietin (PDpoetin10000IU?rh Erythropoietin Alpha)200 units per Kilogram was intravenously injected at the time of the induction of anesthesia. Intervention 2
Prevention
Placebo
Intervention group: Erythropoietin (PDpoetin10000IU?rh Erythropoietin Alpha)200 units per Kilogram was intravenously injected at the time of the induction of anesthesia
control group: Saline was intravenously injected at the time of the induction of anesthesia
Sponsors
Vice chancellor for research, Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria; Patients among the candidates who had an elective coronary artery bypass graft surgery by on pump method. Exclusion criteria; Acute kidney injury prior to the surgery; having erythropoietin prior to coronary artery bypass graft surgery before; uncontrolled blood pressure; erythropoietin allergy; using nephrotoxic drugs before surgery is 3 days.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Creatinin. Timepoint: Before Surgery and 24hr,48hr,72hr after surgery. Method of measurement: Serum creatinin was measured using a Prestige 24i (Tokyo Boeki) device and then was measured by Pars Azmoun kits, the scale was mg/dl. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of pump. Timepoint: Intraoperative. Method of measurement: hour.;The amount of transfused. Timepoint: Intraoperative. Method of measurement: unit.;Blood pressure. Timepoint: Intraoperative. Method of measurement: mmHg.;Urinary output. Timepoint: Intraoperative. Method of measurement: Catheter and cc. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahmood Hosseinzadeh maleki
Birjand University of Medical Sciences
Outcome results
None listed