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Hyaluronic Acid Compared with Corticosteroid Injections for the Treatment of Osteoarthritis of the knee

Hyaluronic Acid Compared with Corticosteroid Injections for the Treatment of Osteoarthritis of the knee

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015031421460N1
Enrollment
140
Registered
2015-08-01
Start date
2015-05-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee Osteoarthritis. Gonarthrosis [arthrosis of knee]

Interventions

Intervention 1: Patients participating in the study will be divided into two groups of 70 people. One group will take 40 mg Depomedrol corticosteroid injection in the space between the knee joint
Treatment - Drugs
intervention group: hyaluronic acid (Hyalgan) in 2 ml vials to the space between the knee joint by an orthopedic physician
control group: this group will take 40 mg Depomedrol corticosteroid injection in the space between the knee joint by an orthopedic physician
Patients participating in the study will be divided into two groups of 70 people. One group will take 40 mg Depomedrol corticosteroid injection in the space between the knee joint by an orthopedic

Sponsors

Vice Chancellor for research of Fasa University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
48 Years to 13 Years

Inclusion criteria

Inclusion criteria: Qualified patients were men and women from 45 years to 80 years of age suffering from knee OA for more than 3 months, with radiographic. Main exclusion criteria were a history or presence of trauma or surgery or cancer or malignant tumors, infections and sores on the target knee, History of vasovagal shock , The use of NSAIDs in 2 days prior to injection, Any receiving corticosteroids injection in the knee in the last 6 months , Pregnancy and lactation

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: before intervention- one- two- three months after intervention. Method of measurement: Visual analogue scale and questionnaire.

Secondary

MeasureTime frame
Physical function. Timepoint: before and after intervention. Method of measurement: questionnaire and interview with patients.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Alireza Askari

Fasa University of Medical Sciences

aaskari60@yahoo.com+98 71 5335 0994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026