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Dual triggering in improving assisted reproductive programs outcome

A comparison of Dual triggering by administration of Gonadotropin releasing hormon agonist plus human chorionic gonadotropin versus HCG in normal responders at assisted reproductive programs outcome

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015031221420N2
Enrollment
223
Registered
2015-06-25
Start date
2014-03-01
Completion date
Unknown
Last updated
2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

female infertility. Female infertility, unspecified

Interventions

Intervention 1: control group receive 6500 I.U hCG IM for triggering final oocyte maturation . Intervention 2: Intervention group receive 6500 I.U. IM hCG+triptorelin0.2mg/sc for triggering.

Sponsors

shahid sadoughi university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 42 Years

Inclusion criteria

Inclusion criteria: normal responder women by tubal or male infertility factor, 18< Body mass index <30 kg/m2, and age =42 yr with the history of infertility for at least 1 yr that were candidate for ART protocol

Exclusion criteria

Exclusion criteria: the presence of endocrine disorders such as diabetes mellitus, hyperprolactinemia, thyroid disorders, congenital adrenal hyperplasia, Cushing syndrome, polycystic ovary syndrome, congenital uterine anomaliesdisorders, repeated implantation failure, day-3 FSH concentration =10 IU/L or serum anti-Mullerian hormone =1.0 ng/mL, and azoospermia

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy rate. Timepoint: 28 days after transfer. Method of measurement: vaginal sonography.

Secondary

MeasureTime frame
Chemical pregnancy rate. Timepoint: 14 days after transfer. Method of measurement: BhCG test.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Eftekhar

Yazd University of Medical Sciences

eftekhar@ssu.ac.ir+98 35 3824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026