The effectiveness of intravenous infusion pump combined with ( dexmedetomidine and acetaminophen ) compared with ( fentanyl and acetaminophen ) for postoperative pain control in patients who have undergone cesarean section.

Comparison of adding dexmedetomidine with fentanyl? to acetaminophen in intravenous patient controlled analgesia (PCA)? for pain after Caesarean section

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201503117984N23

Enrollment

Registered

2016-03-09

Start date

2016-01-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative analgesia. Pain, unspecified

Interventions

Intervention 1: In first group PCIA protocol consisted of 2g Acetaminophen and fentanyl (0.3 mic.g./kg/min for24h)diluted into 100 ml with physiological saline and administered at a continuous infusi

Treatment - Drugs

In first group PCIA protocol consisted of 2g Acetaminophen and fentanyl (0.3 mic.g./kg/min for24h)diluted into 100 ml with physiological saline and administered at a continuous infusion rate of 4 ml/

In second group PCIA protocol consisted of 2g Acetaminophen and dexmedetomidine(0.15 mic.g./kg/h for24h)diluted into 100 ml with physiological saline and administered at a continuous infusion rate

Eligibility

Sex/Gender

Female

Age

20 Years to 38 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Parturient with age between 20 and 38 years who come to Rasool e Akram hospital; Parturients undergoing elective caesarean delivery; American Society of Anesthesiologists (ASA) physical statuses grade I and II; Parturient undergoing neuroaxial(spinal or epidural) anesthesia. Exclusion criteria: Dissatisfaction;Emergency caesarean delivery; American Society of Anesthesiologists (ASA) physical statuses grade more than II; Parturient with age less than 20 and more than 38 years old; Parturient undergoing general anesthesia;A history of opioid analgesic use or tranquilliser use.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: hours: 1-6-12-24. Method of measurement: Visual Analogue Scale.	—

Secondary

Measure	Time frame
Parturient satisfaction. Timepoint: Hour 24. Method of measurement: parturient expression.;Hypotention. Timepoint: Hours 1 - 6 - 12 - 24. Method of measurement: Manometer.;Bradycardia. Timepoint: Hours 1 - 6 - 12 - 24. Method of measurement: Timer.;Nausea and vomiting. Timepoint: Hours 1 - 6 - 12 - 24. Method of measurement: parturient expression.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShakeri Asadollah

Iran University of Medical Science

ashakeri123@yahoo.com+216 4352107

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026