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Effect of Pistacia atlantica subsp. mutica oleo-gum resin, Punica granatum var. pleniflora flowers and Eugenia on halitosis

Preparation and clinical trial of tooth paste contained Pistacia atlantica subsp. mutica oleo-gum resin, Punica granatum var. pleniflora flowers and Eugenia caryophyllata buds for halitosis

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015030921395N1
Enrollment
80
Registered
2016-08-30
Start date
2016-01-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Halitosis. Halitosis

Interventions

Intervention 1: herbal toothpaste have been used for two weeks in oral cavity. Intervention 2: placebo is used in oral cavity for 2 weeks.
Treatment - Drugs
Placebo
herbal toothpaste have been used for two weeks in oral cavity.
placebo is used in oral cavity for 2 weeks.

Sponsors

Vice Chancellor for research of Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: inclusion criteria: Organoleptic score =2; Tongue coating score =4 exclusion criteria: smoking; alcohol; systemic disease; medicinal causing dry month; use of antibiotics in the past month; Eating spicy foods, onions and garlic in the 48 hours prior to the examination; Using orthodontic appliance (fixed and mobile) and mobile dentures; diabetes; metabolic disease; infections of the upper respiratory tract; kidney and liver failure, chronic inflammatory diseases; surgery of the head and neck malignancies; anticoagulation therapy such as aspirin; heparin; warfarin. ?

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Halitosis. Timepoint: 2 weeks. Method of measurement: plaque index, bleeding index and halitosis check list.

Secondary

MeasureTime frame
Microbial contamination. Timepoint: 2 weeks. Method of measurement: microbial contamination of salivary.;Aproximal plaque index. Timepoint: 2 weeks. Method of measurement: aproximal plaque index.;Tounge coating. Timepoint: 2 weeks. Method of measurement: tounge coating.;Sulcus bleeding index. Timepoint: 2 weeks. Method of measurement: sulcus bleeding index.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtefeh Arabzadeh

Shiraz University of Medical Sciences

arabzade_a@sums.ac.ir+98 71 3242 4128

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026