The Efficacy Of DDAVP, Tramadol and Indomethacin in Alleviating the Pain In Acute Renal Colic

Comparison of The Efficacy Of DDAVP, Tramadol and Indomethacin in Alleviating the Pain In Patients With Acute Renal Colic

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015030919470N18

Enrollment

120

Registered

2015-03-14

Start date

2005-06-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Renal Colic. Unspecified renal colic

Interventions

Patients in group B, received desmopressin 40 microgram intranasally for alleviating the pain

Intervention 1: Patients in group A, received tramadol 50mg intramuscularly for alleviating the pain. Intervention 2: Patients in group B, received desmopressin 40 microgram intranasally for alleviati

Treatment - Drugs

Patients in group A, received tramadol 50mg intramuscularly for alleviating the pain

Patients in group C, received indomethacin 100mg rectally for alleviating the pain

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria:120 patients (70 men and 50 women, mean age 38.2 years) referring to emergency room with renal colic caused by lithiasis without any previous treatment. exclusion criteria: Patients with evidence of high blood pressure, coronary disease, rhinitis, influenza, anticoagulant therapy, peptic ulcer, renal or liver failure were excluded from the study, as were any pregnant women.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
To investigate the amount of pain after tramadol 50mg intramuscular in acute renal colic. Timepoint: on the admission and 30 minutes after therapy administration. Method of measurement: VAS scale.;To investigate the amount of pain after desmopressin 40 microgram intranasally in acute renal colic. Timepoint: on the admission and 30 minutes after therapy administration. Method of measurement: VAS scale.;To investigate the amount of pain indomethacin 100mg rectally in acute renal colic. Timepoint: on the admission and 30 minutes after therapy administration. Method of measurement: VAS scale.	—

Measure

Time frame

To investigate the amount of pain after tramadol 50mg intramuscular in acute renal colic. Timepoint: on the admission and 30 minutes after therapy administration. Method of measurement: VAS scale.;To investigate the amount of pain after desmopressin 40 microgram intranasally in acute renal colic. Timepoint: on the admission and 30 minutes after therapy administration. Method of measurement: VAS scale.;To investigate the amount of pain indomethacin 100mg rectally in acute renal colic. Timepoint: on the admission and 30 minutes after therapy administration. Method of measurement: VAS scale.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Aminsharifi

Shiraz University of Medical Sciences

aminsharifi_ar@yahoo.com+98 71 3233 0724

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026