Epilepsy. Episodic diseases
Conditions
Interventions
Intervention 1: Control Group: carbamazepine group: This group will be treated with carbamazepine. In carbamazepine group,the drug with the dose of 5 mg/kg/day is initiated and increases 5 mg/kg/wee
Treatment - Drugs
Control Group: carbamazepine group: This group will be treated with carbamazepine. In carbamazepine group,the drug with the dose of 5 mg/kg/day is initiated and increases 5 mg/kg/week. finlay, it re
Intervention Group: levetiracetam group: This group will be treated with levetiracetam. In levetiracetam group,the drug with the dose of10 mg/kg per day is initiated and increases 10 mg/kg/week . fi
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 16 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Children with age over one year and less than sixteen years old with newly diagnosed focal epilepsy, No history of refractory seizures, No history of renal disease, No history of hepatic disease, No history of cerebral palsy, No history of antiepileptic drug consumption. Exclusion criteria: Pseudo- seizures, Skin rash especially Stevens Johnson syndrome, Drug-induced hepatitis, Acute psychosis, Renal disorders, Severe agitation, any other mild side effects that is unbearable to the patient or parents
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Occurence of seizure. Timepoint: Six months from the beginning of study. Method of measurement: Desciption of patients and parents. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rise of liver enzymes. Timepoint: One month after beginning of the study. Method of measurement: Measurment of AST and ALT.;Skin rash. Timepoint: In the six month from the beginning of the study. Method of measurement: Observation.;Agitation. Timepoint: In the six month from the beginning of the study. Method of measurement: Parents report.;Somnolence. Timepoint: In the six month from the beginning of the study. Method of measurement: Parents report.;Advers blood effects. Timepoint: One montn after beginning of study. Method of measurement: CBC examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHosein Eslamiyeh
Mashhad University of Medical Sciences
Outcome results
None listed