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Impact of fullring and cross-linking in treatment of keratoconus

Comparsion of efficacy of afull ring insertion with and without simultaneous cross-linking in patients with keratoconus using femtosecond laser

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015030813567N9
Enrollment
60
Registered
2015-08-23
Start date
2015-06-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

keratoconus. other disorders of cornea

Interventions

Intervention 1: Thirty eyes of thirty patients were into trial group . In trial group will use fullring with simultaneous cross-linking.In this group using femtosecond laser,pocket in the corneal str
Treatment - Surgery
Thirty eyes of thirty patients were into trial group . In trial group will use fullring with simultaneous cross-linking.In this group using femtosecond laser,pocket in the corneal stroma at a depth o
Thirty eyes of thirty patients were in to control group. In the control group will use the only fullring.In this group using femtosecond laser,pocket in the corneal stroma at a depth of 300 microns an

Sponsors

Vice chancellor for research, Tehran University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
73 Years to 59 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria: Older than 21 year and less than 35 year ; Glasses or hard contact lens intolerance ; mean keratometery less than 53 diopter ; Central corneal thickness more than 400 micron ; maximum myopia and astigmatism 10 diopter ; Best corrected visual acuity more than 4/10 The exclusion criteria: Central corneal scar ;History of any ocular surgery ;pregnancy and lactation ;History of herpetic keratitis ;History of cross-linking ;Patients with connective tissue diseases

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Visual acuity. Timepoint: Before intervention-one week,one month,three month and six month after intervention. Method of measurement: snellen chart.;Refractive error. Timepoint: Before intervention-one week,one month,three month and six month after intervention. Method of measurement: Retinoscopy.;Keratometery. Timepoint: Before intervention-one week,one month,three month and six month after intervention. Method of measurement: Pentacam.;Corneal high order aberration. Timepoint: Before intervention-one week,one month,three month and six month after intervention. Method of measurement: iTrace.;Depth position of the full ring in corneal stroma. Timepoint: Before intervention-one week,one month,three month and six month after intervention. Method of measurement: OCT Casia.;Corneal endothelial cell count. Timepoint: Before intervention-one week,one month,three month and six month after intervention. Method of measurement: Specular microscopy.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmehrdad mohammadpour

Tehran university of medical sciences

MAHAMMADPOUR@yahoo.com+98 21 5542 1006

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026