lowerlimb surgery. Disorders of continuity of bone
Conditions
Interventions
Intervention 1: Intervention Group 1 (Spinal Anesthesia): A blood sample will be collected before anesthesia. The patient will undergo spinal anesthesia. Before surgery and 12 and 48 hours after surge
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
25 Years to 65 Years
Inclusion criteria
Inclusion criteria: ASA grade I or II Age range of 25 to 65 years use of tourniquet on the lower limbs of one side absence of vascular disease no cardio respiratory disease absence of renal failure non-impairment in liver function non-diabetes or the use of any antioxidant or anti-inflammatory drug
Exclusion criteria
Exclusion criteria: Duration of surgery less than 60 minutes or more than 90 minutes Need for re-operation patient's unwillingness to cooperate in each stage of study patient's death
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum level of Interlukin 6. Timepoint: Before using tourniquet (T0), 12 hours after surgery (T1), and 48 hours after surgery (T2). Method of measurement: ELlSA.;TNFA. Timepoint: Before using tourniquet (T0), 12 hours after surgery (T1), and 48 hours after surgery (T2). Method of measurement: ELlSA.;Hs-CRP. Timepoint: Before using tourniquet (T0), 12 hours after surgery (T1), and 48 hours after surgery (T2). Method of measurement: ELlSA.;Ferritin. Timepoint: Before using tourniquet (T0), 12 hours after surgery (T1), and 48 hours after surgery (T2). Method of measurement: ELlSA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Amir Sabertanha
Birjand University of Medical Sciences
Outcome results
None listed