luteal phase support in IUI cycles.
Conditions
Interventions
Intervention 1: In all patients ovarian stimulation was started on the third day of menstrual cycle after the basal transvaginal ultrasonography with 2/5 mg letrozole (letrofom, Aburaihan, Tehran, Ira
Organon, Oss, Netherlands) was given intramuscularly to induce final follicular maturation. IUI was taken with a disposable catheter (Wallace,Coopersurgical, Inc, USA) 35-36 hr after the HCG administr
for 2 weeks after IUI and in the event of pregnancy, progesterone was kept on for eight weeks of gestation. Intervention 3: After ovarian stimulation according to intervention 1 for luteal phase sup
for 2 weeks after IUI and in the event of pregnancy, progesterone was kept on for eight weeks of gestation. Intervention 4: After ovarian stimulation according to intervention 1 for luteal phase sup
Sponsors
Vice Chancellor for Research and Technology, Semnan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
20 Years to 38 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 20-38yr,period of infertility more than 1year.with unexplained or male factor infertility undergoing IUI cycle were included. With normal Thyroid- stimulating- Hormone (TSH) and prolactin levels. Bilateral patent tubes at HSG or laparoscopy, normal hormonal assay in the early follicular phase, and normal sperm count, motility, and morphology according to the World Health Organization (WHO 1992) criteria for unexplained infertility. In male-factor infertility cases, the total motile sperm count had to be > 1 million to be considered eligible to enter the study
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Pregnancy. Timepoint: 5 Weeks after IUI. Method of measurement: Trans vaginal sonography will be done at 5 weeks after IUI. | — |
Secondary
| Measure | Time frame |
|---|---|
| Abortion and twin pregnancy. Timepoint: From confirmed pregnancy to12 weeks of gestation . Method of measurement: Sonography.;Ongoing pregnancy. Timepoint: From confirmed pregnancy to12 weeks of gestation . Method of measurement: Vaginal sonography.;The satisfaction and convenience rate between vaginal progesterone and IM progesterone. Timepoint: From confirmed pregnancy to8 weeks of gestation. Method of measurement: Using a scale of 1-3, with 3 being very satisfied, convenient; 2 being satisfied, convenient; and 1 being unsatisfied, not convenient.;Side effects of vaginal and IM progestrone. Timepoint: From confirmed pregnancy to8 weeks of gestation. Method of measurement: Vaginal itching , discharge and pain and swelling on the injection site . | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Gohar Joraablo
Semnan University of Medical Sciences
Outcome results
None listed