Condition 1: infertile patients. Condition 2: infertility. Female infertility Male infertility
Conditions
Interventions
Intervention 1: Intervention: assisted laser hatching and microsurgery on embryo for removal the fragments or granules surrounded the blastomeres. Intervention 2: control: without any intervention.
Intervention: assisted laser hatching and microsurgery on embryo for removal the fragments or granules surrounded the blastomeres
Sponsors
Shahid Sadoughi University of Medical Sciences, Yazd
Eligibility
Sex/Gender
Female
Age
17 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: All patients undergoing IVF/ICSI who have fragmented vitrified-warmed days 2 or 3 embryos with morphology grades of B and C. Exclusion criteria: Patients with multi-nucleated or revitrified-warmed embryos
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chemical pregnancy. Timepoint: 14 days after transfer of embryos into uterine. Method of measurement: measuring bhCG level in blood.;Clinical pregnancy. Timepoint: heart beat in 7th week of gestation. Method of measurement: observation of heart beat with ultrasound. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cell division in embryo. Timepoint: overnight after vitrified embryo warming. Method of measurement: by inverted microscope. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSomayyeh Safari
Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd
Outcome results
None listed