General anesthasia. Other complications of anaesthesia
Conditions
Interventions
IV. Intervention 2: Thiopental sodium, 5 mg/kg within 30 seconds
IV. Intervention 3: Etomidate, 0.3 mg/kg within 30 seconds
Treatment - Drugs
Propofol, 2.2 mg/kg within 30 seconds
Thiopental sodium, 5 mg/kg within 30 seconds
Intervention 1: Propofol, 2.2 mg/kg within 30 seconds
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
17 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age of 17-80; American Society of Anesthesiologist (ASA) I and II classes; no history of hypertension; no history of cerebrovascular accidents; no food allergy (especially to soya and egg); no history of acute porphyria Exclusion criteria: air way obstruction; laryngospasm; need to re-intubation after laryngoscope excitation; systolic blood pressure five minutes after induction of anesthesia less than 90 mmHg; surgery duration more than 30 minutes
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diastolic blood pressure. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: mm-Hg, sphygmomanometer.;Systolic blood pressure. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: mm-Hg, sphygmomanometer.;Heart rate. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: Electrocardiogram monitor.;O2 saturation. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: Pulseoxymeter.;Surgeon's satisfaction of surgery. Timepoint: After the surgery. Method of measurement: Questionnaire.;Time of surgery. Timepoint: Operation's time duration. Method of measurement: Timer.;Time of recovery hospitalization. Timepoint: Recovery duration. Method of measurement: Timer.;Mean arterial pressure. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: mm-Hg, sphygmomanometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotension. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: mm-Hg, sphygmomanometer.;Tachycardia. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: Electrocardiogram monitor.;Hypertension. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: mm-Hg, sphygmomanometer.;Bradycardia. Timepoint: Before and during intervention and after recovery time. 1, 3, 5, 10, 15 min after drug injection and 3, 5, 15, 30 min after recovery. Method of measurement: Electrocardiogram monitor. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mehrdad Masoudifar
Isfahan University of Medical Scineces
Outcome results
None listed