Comparison of the Effects of Two Methods of General Anesthesia and Epidural Anesthesia During Lumbar Laminectomy Surgery

Comparison of Hemodynamic Changes and Side Effects Due to Two Methods of General Anesthesia and Epidural Anesthesia in Patients Undergo Lumbar Laminectomy Surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015030419037N7

Enrollment

Registered

2015-03-15

Start date

2014-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Heart rate instability due to anesthesia. Condition 2: Blood pressure instability due to anesthesia.

Interventions

Intervention 1: First intervention group: Intravinously injection of Midazolam (Ampoule 5 mg/ml from Aburaihan drug manufacturing company, Iran) (0.1 to 0.3 mg/kg) and Fentanyl (Ampoule 50 from Pharma

Treatment - Other

First intervention group: Intravinously injection of Midazolam (Ampoule 5 mg/ml from Aburaihan drug manufacturing company, Iran) (0.1 to 0.3 mg/kg) and Fentanyl (Ampoule 50 from Pharmaceutical drug m

Second intervention group: Epidural injection of Lidocain (Ampoule 20 mg/ml from Aburaihan drug manufacturing company, Iran) (2-3 ml) for spinal anesthesia using 25 Gauge Quincke spinal needle in L3-

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients between 30 to 60 years of age who are candidate for lumbar laminectomy surgery and are categorized in ASA class 1 (The American Society of Anesthesiologists Physical Status classification system): Normal healthy patients with no organic, physiologic, or psychiatric disturbance. Exclusion criteria: Patients who use anti-hypertensive, analgesic or sedative agents; patients who are not NPO (nil per os); no patient's tendency for epidural anesthesia; obesity; presence of epidural anesthesia contraindications.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mean heart rate. Timepoint: From the beginning of anesthesia every 5 minutes until 1 hour after surgery. Method of measurement: Monitor device.;Mean blood pressure. Timepoint: From the beginning of anesthesia every 5 minutes until 1 hour after surgery. Method of measurement: Monitor device.	—

Secondary

Measure	Time frame
Post operation pain. Timepoint: From the beginning of surgery every 2 hours until 6 hours after the surgery. Method of measurement: Visual Analogue Scale questionnaire (VAS).;Nasea and vomitting. Timepoint: During recovery time. Method of measurement: Objective.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Masoumeh Hosseyni Valami

Qazvin University of Medical Sciences

yusefi.mahdieh@yahoo.com+98 28 3333 6004

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026