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The effect of neurofeedback with pharmacotherapy in treatment of patients with obsessive – compulsive disorder

The effect of neurofeedback with pharmacotherapy on cognitive ability and executive function in patients with obsessive – compulsive disorder

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015030321313N1
Enrollment
45
Registered
2015-03-11
Start date
2015-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obsessive – compulsive disorder. Obsessive-compulsive disorder

Interventions

Intervention 1: Group 2: In this group patients will receive placebo Neurofeedback 2 times per week for 10 weeks and they also will receive sertraline 20-40 mg per day for 16 weeks. Intervention 2:
Treatment - Drugs
Group 3: In this group patients will receive sertraline 10 mg per day for 16 weeks.
Group 1: In this group patients will receive Neurofeedback 2 times per week For 10 weeks and they also will receive sertraline 20-40 mg per day for 16 weeks
Group 2: In this group patients will receive placebo Neurofeedback 2 times per week for 10 weeks and they also will receive sertraline 20-40 mg per day for 16 weeks

Sponsors

Vice chancellor for research and Technology, Hamadan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Diagnosis of obsessive-compulsive disorder based on the psychiatrist's interview According to DSM-5 criteria, Taking sertraline, Be at least 18 and up to 60 years, The ability to read and write, A minimum score of 16 on the Yale Brown Obsessive Compulsive Scale. Exclusion criteria: The people with acute and serious mental disorders such as bipolar disorder, schizophrenia, etc, People with other medical illnesses such as head injuries, Neurologic Diseases, drug allergies, A history of substance abuse, The types of dementia and cognitive disabilities.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of symptoms of OCD. Timepoint: before and after the intervention. Method of measurement: Y_BOCS and CGI Scale.

Secondary

MeasureTime frame
Cognitive ability and executive function. Timepoint: before and after the intervention. Method of measurement: Wisconsin, Stroop and Pasat tests.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaeid Yazdi-Ravandi

Hamadan Universiety of Medical Sciences

saeid_yazdiravandi@yahoo.com+98 81 3827 1066

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026