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Effect of Propofol on vital signs and assessing the level of anesthesia

Comparison of different doses of propofol on hemodynamics symptoms and bispectral index (BIS) in patients undergoing induction of anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015030218099N3
Enrollment
92
Registered
2015-05-23
Start date
2015-03-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anesthesia. Dissociative anaesthesia and sensory loss

Interventions

Intervention 1: In the first interventional group 46 patients receive intravenous propofol in a dose of one mg per kg of weight(Ampoules made in Iran by drug Behestan Co.) for anesthesia induction.
Treatment - Drugs
In the first interventional group 46 patients receive intravenous propofol in a dose of one mg per kg of weight(Ampoules made in Iran by drug Behestan Co.) for anesthesia induction. Dose of 3 mg pe
In the second interventional group, 46 patients receive intravenous propofol in a dose of 2.5 mg per kg of weight(Ampoules made in Iran by drug Behestan Co.) for anesthesia induction. Dose of 3 mg

Sponsors

Vice chancellor for research, Shahrekord University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Aged between 20 and 80 years old, patients under surgery with general Anesthesia, patients with class I and ASA class II. Exclusion criteria: any observable unpredictable complications after injection of propofol; patients with ASA class higher than I and II, patients with drug sensitivity, and patients with contraindications due to the use of this drug.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Movement Score. Timepoint: 1 min after the induction of anesthesia. Method of measurement: observation.;Blood pressure. Timepoint: 5 min before induction of anesthesia,1 min and 5min after induction of anesthesia and after intubation. Method of measurement: monitoring devices.;Level of consciousness. Timepoint: 5 minutes before induction of anesthesia, 1 minute and 5 minutes after intervention and after intubation. Method of measurement: BIS monitoring set.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Gholamreza Shabanian

Shahrekord University of Medical Sciences

gshabanian@skums.ac.ir+98 38 3222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026