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Effectiveness of Complementary Medicine in Improving Pain, Fatigue and Sleep Disorder in Patients with Cancer

Comparison of the effect of massage therapy with acupressure on the symptom cluster of pain, fatigue and sleep disorder in patients with advanced cancer: A 2x2 factorial trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150302021307N7
Enrollment
100
Registered
2024-10-09
Start date
2025-04-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Fatigue. Condition 2: Pain. Condition 3: Sleep disorder. Chronic fatigue, unspecified Other chronic pain Sleep disorders not due to a substance or known physiological condition

Interventions

Intervention 1: Fourth intervention group: will receive 30-minute massage sessions 3 times a week for four weeks. Intervention 2: Second intervention group: will receive 30-minute acupressure sessions

Sponsors

Ahvaz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years with advanced cancer diagnosis Experience the intensity of pain, fatigue and sleep disorder 4 or more in the last 24 hours (according to a numerical rating scale of 0 to 10) before the intervention The patient's platelet level should be above 15,000 per cubic millimeter

Exclusion criteria

Exclusion criteria: The existence of a known disorder of pain, fatigue and sleep that is mentioned in the patient's medical history and is not caused by cancer Underlying comorbidities such as diabetes, peripheral nerve disease and skin problems in the massage area have treatment in the tumor area or the cancer has spread to the bones Rheumatoid arthritis, spinal cord injury, or bone disease that may worsen with physical manipulation The presence of varicose veins

Design outcomes

Primary

MeasureTime frame
The intensity of symptom cluster of pain, fatigue and sleep disorder. Timepoint: The intensity of symptom cluster will be measured at baseline, weekly during the 4-week intervention period, and sixth and eighth weeks as follow-up. Totally, symptom cluster intensity will be measured for 7 times. Method of measurement: Symptom cluster intensity will be measured using pain, fatigue, and sleep disorder items. The measurement tool is a numerical rating scale of 0-10. The mean scores of the three symptoms will be calculated as the symptom cluster intensity.

Secondary

MeasureTime frame
Analgesic received. Timepoint: The analgesic received will be measured at baseline, weekly during the 4-week intervention period, and sixth and eighth weeks. Totally, analgesic received will be measured for 7 times. Method of measurement: The analgesic received in the last 24 hours will be documented by the patient in the diary.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMojtaba Miladinia

Ahvaz University of Medical Sciences

miladinia.m@ajums.ac.ir+98 61 3311 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026