The levels of oxidative stress biomarkers during labor

Relationship between serum and salivary biomarkers of oxidative stress during delivery and neonatal outcome in Fatemieh

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201502266888N7

Enrollment

Registered

2015-05-16

Start date

2015-02-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biomarkers of oxidative stress during labor. Certain conditions originating in the perinatal period

Interventions

Intervention 1: Control group: Usual care or no intervention will receive. Intervention 2: Group Intervention: The intervention consisted of a combination of local anesthesia administered during the a

Diagnosis

Control group: Usual care or no intervention will receive

Group Intervention: The intervention consisted of a combination of local anesthesia administered during the active phase of labor and 3-4 cm cervical dilatation. we used of Marcaine with a concentrat

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: The absence of acute and chronic complications of pregnancy and labor, singleton pregnancy full term pregnancy, lack of indications for cesarean Exclusion criteria: the unwillingness of parents to continue to participate in the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Total Antioxidant capacity. Timepoint: After the intervention at 8-9 cm dilatation. Method of measurement: In umol / ml by using FRAP.;Catalase enzyme. Timepoint: After the intervention at 8-9 cm dilatation. Method of measurement: In umol / ml by using TBA.;Thiol groups. Timepoint: After the intervention at 8-9 cm dilatation. Method of measurement: In MMol by using laboratory techniques.	—

Secondary

Measure	Time frame
Hypotension. Timepoint: Continuous monitoring of blood pressure after the intervention up to 2 hours after delivery. Method of measurement: pressure on the Mm Hg using a sphygmomanometer.;Hyperthermia. Timepoint: Continuous monitoring of body temperature after intervention Up to 2 hours postpartum. Method of measurement: body temperature in Mm Hg using an oral thermometer.;Increasing duration of delivery. Timepoint: Every two hours after the intervention. Method of measurement: Partograghy form.	—

Measure

Time frame

Hypotension. Timepoint: Continuous monitoring of blood pressure after the intervention up to 2 hours after delivery. Method of measurement: pressure on the Mm Hg using a sphygmomanometer.;Hyperthermia. Timepoint: Continuous monitoring of body temperature after intervention Up to 2 hours postpartum. Method of measurement: body temperature in Mm Hg using an oral thermometer.;Increasing duration of delivery. Timepoint: Every two hours after the intervention. Method of measurement: Partograghy form.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Shobeiri

Hamadan University of Medical sciences

vc_research@umsha.ac.ir+98 81 3838 0150

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026