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The effect of Licorice lozenges on chronic cough treatment

Randomized Double-blind Clinical Trial: The effect of Licorice lozenges vs. placebo on chronic cough treatment

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015022421220N1
Enrollment
60
Registered
2015-11-22
Start date
2014-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Cough. Cough-chronic

Interventions

Intervention 1: Intervention Group: Licorice lozenges/day for 2 weeks. Patients will be followed at Baseline, 2 weeks and one month after starting intervention. Intervention 2: Placebo Group: Placebo
Treatment - Drugs
Placebo
Intervention Group: Licorice lozenges/day for 2 weeks. Patients will be followed at Baseline, 2 weeks and one month after starting intervention.
Placebo Group: Placebo lozenges/day for 2 weeks. Patients will be followed at Baseline, 2 weeks and one month after starting intervention.

Sponsors

Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients between 18-70 years old; with resistant idiopathic chronic cough for more than 8 weeks; written informed consent to participate in the project Exclusion criteria: any allergic reaction to the drug; asthma; COPD; GERD; Rhinitis; pregnancy and lactation; hypertension; arrhythmia; Zollinger syndrome; mineralocorticoid and anticoagulants consumers; pregnancy during the study; the drug lost more than three doses; increasing in blood pressure during the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cough severity. Timepoint: Baseline. Method of measurement: Leicester cough questionnaire.

Secondary

MeasureTime frame
Cough severity. Timepoint: 2 weeks after treatment and 2 weeks after the end of intervention. Method of measurement: Leicester Cough Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hajar Ghaemi

Shiraz University of Medical Sciences

haghaemi@sums.ac.ir+98 71 3647 4376

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026