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Effect of "Punica granatum" fruit and " mentha spicata" on nausea and vomiting in pregnancy

Assessment of the effect of a product of "Punica granatum" fruit and " mentha spicata" on nausea and vomitting in pregnancy

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015022221186N1
Enrollment
70
Registered
2015-11-20
Start date
2015-09-15
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nausea and vomiting of pregnancy. Vomiting of pregnancy, unspecified

Interventions

Intervention 1: Intervention: syrup of Pomegranate fruit and Mentha spicata, Prepared in the herbarium of Institute of History of Medicine, Islamic and Complementary Medicine Iran University of Medica
Treatment - Drugs
Intervention: syrup of Pomegranate fruit and Mentha spicata, Prepared in the herbarium of Institute of History of Medicine, Islamic and Complementary Medicine Iran University of Medical Sciences, 5
Control group: Vitamin B-6 20 mg tablet (Production of pharmaceutical company Ramvfarmyn Tehran) three times daily before meals for one week

Sponsors

Faculty of Traditional Medicine,Traditional Medicine Research Center, Kerman University of Medical S
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age 18-40 years, gestational age 6-16 weeks, singleton pregnancy with live fetus based on ultrasound, moderate nausea and vomiting of pregnancy (7-13 score of PUQE 24 Questionnaire), Patient Satisfaction, the possibility follow-up the patient, ability to read and write, at least 24 hours before the visit did not take anti-nausea drug. Exclusion criteria: severe nausea and vomiting during pregnancy that may require fluid therapy and hospitalization, nausea and vomiting of pregnancy by secondary causes: peptic ulcer, hepatitis, pyelonephritis,... multiple pregnancy, ectopic pregnancy, mole, presence of pregnancy complications such as bleeding, threatened abortion, history of chronic disease, history of drug addiction, alcoholism and smoking, history of drug allergy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Severity of nausea. Timepoint: Before, one week during intervention and one week after intervention. Method of measurement: VAS (Visual Analogue Scale).;Nausea time. Timepoint: Before intervention, one week during intervention and one week after intervention. Method of measurement: PUQE 24 hours questionnaire.;Vomiting times. Timepoint: Before intervention, one week during intervention and one week after intervention. Method of measurement: PUQE 24 hours questionnaire.;Retching times. Timepoint: Before intervention, one week during intervention and one week after intervention. Method of measurement: PUQE 24 hours questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahrbanoo Abdolhosseini

Faculty of Traditional Medicine, Kerman University of Medical Sciences

sh-abdolhosseini@razi.tums.ac.ir+98 34 3312 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026