Delirium. Delirium due to known physiological condition
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, in addition to standard supports, one intravenous vitamin B12 injection ( 1000 micrograms) will be administered daily for 3 days. Interve
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients (18 years and older) at the time of admission to the Intensive Care Unit (ICU) No history of delirium, mood disorders, or alcohol dependence prior to ICU admission An estimated minimum of 7 days of ICU stay A risk of delirium based on the PREDELIRIC score equal to or greater than 40% at the time of study entry Absence of visual and hearing impairments Absence of liver failure
Exclusion criteria
Exclusion criteria: Patients with GCS= 8 patients with a score of -4 or -5 on The Richmond Agitation-Sedation Scale (RASS) Any condition that makes delirium assessment based on the CAM-ICU index for at least 5 days impossible Inability to collect samples for evaluating vitamin B12 levels at the end of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of delirium. Timepoint: Daily evaluation of delirium incidence for 7 days following study recruitment. Method of measurement: Calculate Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShadi Farsaei
Esfahan University of Medical Sciences
Outcome results
None listed