Major depression. Major Depressive episode
Conditions
Interventions
Intervention 1: Citalopram 40 mg /day plus capsule citicolin 100 mg BID as the main drug for six weeks as the intervention group. Intervention 2: Citalopram 40 mg/day plus Placebo for six weeks as th
Treatment - Drugs
Placebo
Citalopram 40 mg /day plus capsule citicolin 100 mg BID as the main drug for six weeks as the intervention group
Citalopram 40 mg/day plus Placebo for six weeks as the control group
Sponsors
Tehran Medical Sciences University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: aInclusion criteria: age between 18 – 50 years old; diagnoses are done on the basis of Diagnostic & Statistical Mental Disorders (DSMD); HRSD score above14; signing informed consent. Exclusion criteria: demise of a close relative; having other psychocognitive affliction; taking antidepressive & psychoactive drugs within the last two months; heart complication; thyroid complication; history of ECT (Electroconvulsive Therapy); alcohol & drug addiction; reaching menopause age; pregnancy and lactation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of depression. Timepoint: Assessment in first and on 2th, 4th and 6th weeks after onset of receiving medication. Method of measurement: Measurment by HAMD. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Shahin Akhondzadeh
Tehran University of Medical Sciences
Outcome results
None listed