Condition 1: Heart rate instability due to anesthesia. Condition 2: Blood pressure instability due to anesthesia.
Conditions
Interventions
Intervention 1: First intervention group (trial):
Receiving handmade drug, Ketofol: 10 ml Propofol solution (10 mg/ml, from Fresenius Kabi drug manufacturing company, Germany) with 10 ml Ketamin solut
First intervention group (trial):
Receiving handmade drug, Ketofol: 10 ml Propofol solution (10 mg/ml, from Fresenius Kabi drug manufacturing company, Germany) with 10 ml Ketamin solution (50 mg/ml,
Second intervention group (control):
Receiving Propofol solution (10 mg/ml, from Fresenius Kabi drug manufacturing company, Germany). One dose of this drug was admitted for the patients intravenously
Sponsors
Investigator
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patients between 20 to 60 years of age who are candidate for laparotomy (including appendectomy, gastrectomy, cholecystectomy and other kinds of laparotomy) under general anesthesia and are in ASA class 1 (The American Society of Anesthesiologists Physical Status classification system): Normal healthy patients with no organic, physiologic, or psychiatric disturbance. Exclusion criteria: Patients who use cardiac or anti-hypertensive or analgesic or sedative agents, patients who are not NPO (nil per os), diabetic or pregnant patients.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean heart rate. Timepoint: In 4 times: before induction, 3, 5 and 10 minutes after induction. Method of measurement: The monitor device.;Mean systolic pressure. Timepoint: In 4 times: before induction, 3, 5 and 10 minutes after induction. Method of measurement: The monitor device.;Mean diastolic pressure. Timepoint: In 4 times: before induction, 3, 5 and 10 minutes after induction. Method of measurement: The monitor device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Hamid Kayalha
Qazvin University of Medical Sciences
Outcome results
None listed