Skip to content

Use of probiotics in icter

Comparison of the effect of probiotics vs. placebo in decreasing hospitalization duration in infants with hyperbilirubinaemia: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015021817413N11
Enrollment
50
Registered
2015-09-16
Start date
2015-07-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Physiologic Jaundice. Physiological jaundice (intense)(prolonged) NOS

Interventions

Intervention 1: Intervention group: will be treated by a half capsule of Prokid probiotic once a day before breast feeding till discharge. Intervention 2: Control group: will use placebo, which is hal
Treatment - Drugs
Intervention group: will be treated by a half capsule of Prokid probiotic once a day before breast feeding till discharge.
Control group: will use placebo, which is half capsule filled with probiotic-free formula with the same color as the Prokid probiotic, once a day before breast feeding till discharge.

Sponsors

Baqiyatallah University of Medical Sciences, Deputy of Research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Days to 28 Days

Inclusion criteria

Inclusion criteria: Inclusion criteria: Gestational age of more than 35 weeks; birth weight of more than 2500 gr; serum level of bilirubin more than 15 mg/dL; direct bilirubin of less than 1.5 mg/dL. Exclusion criteria: Infants less than 2 days of age; ill and septic patients; infants with positive Coombs test; those undergoing blood exchange or IVIG and phenobarbital therapy; patients needing serum therapy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hospitalization duration. Timepoint: after beginning treatment till discharge. Method of measurement: Days Hospitalized after treatment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hossein Khosravi

Students’ Research Committee (SRC), Baqiyatallah University of Medical Sciences, Tehran, IR Iran

m.hosseinkhosravi@yahoo.com+98 21 8126 4354

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026