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The effect of diphenhydramine on recovery complications in tempolanoplasty surgery.

The effect of pre-treatment with diphenhydramine on the complications of recovery in minor ear, nose and throat surgeries (tympanoplasty).

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150217021121N4
Enrollment
100
Registered
2020-04-28
Start date
2020-04-20
Completion date
Unknown
Last updated
2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Postoperative nausea and vomiting. Condition 2: Postoperative pain. Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure Other complications of anesthesia

Interventions

Intervention 1: Intervention group:In this group, 25 mg of diphenhydramine will be injected before the start of anesthesia. Intervention 2: Control group:In this group only 5 cc normal saline (as a pl

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Conscious patients over the age of 18 with ASA grade,class I&II Lack of sensitivity to the study drug

Exclusion criteria

Exclusion criteria: Having middle ear disease Patients with a history of pelvic surgery History of nausea and vomiting over the past 24 hours Pregnant and breastfeeding woman

Design outcomes

Primary

MeasureTime frame
Severity of postoperative nausea and vomiting. Timepoint: Recovery and at 3, 6, 12,18 and 24 hours postoperatively. Method of measurement: scoring by (0=non, 1=nausea, 2=vomiting, 3=vomiting >2 times).;Severity of postoperative pain. Timepoint: Recovery and at 3, 6, 12,18 and 24 hours postoperatively. Method of measurement: Four Numerical Verbal Rating Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Movvassaghi

Tabriz University of Medical Sciences

rz_movassaghi@yahoo.com+98 41 3334 1994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026