Condition 1: Coronary Artery By[pass Grafting. Condition 2: Opium Abuse. Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris Drug abuse counseling and surveillance of drug abuser
Conditions
Interventions
Intervention 1: Patients randomly divided into two groups according to the random numbers table. In the case group, the dexmedtomdin is administered at 1 µg / kg body weight in 15 minutes and then 0.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients with oral opium abuse undergoing elective off pump coronary artery bypass grafting
Exclusion criteria
Exclusion criteria: Use of Cardiopulmonary Pump Life threatening Arrhythmias Massive intraoperative Bleding Requring More Than 1 Unit of Packed RBC Use of Intraaortic Balloon Pump Need for High Dose Vasopressors Decline of Consent Sensitivity to Dexmedetomidine Ejection Fraction Less Than 30%
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain Severity. Timepoint: Every 1 hour. Method of measurement: NSR-CPOT.;Frequence of delireum. Timepoint: Every 8 hour. Method of measurement: ICAM.;Duration of Mechanical Ventilation. Timepoint: Every 1 hour. Method of measurement: Cornometer.;Need for Additional Opiates. Timepoint: Every 1 hour. Method of measurement: Dose Drug. | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal Failur. Timepoint: Daily until admitted. Method of measurement: Cratenin/ out put. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahram Amini
Mashhad University of Medical Sciences
Outcome results
None listed