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The effect of duration of treatment with valganciclovir in children with renal transplantation

Clinical trial of comparision of 3and 6 months prophylaxis with valganciclovir for prevention of cytomegalovirus(CMV) disease in children with renal transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015021321062N1
Enrollment
86
Registered
2015-05-12
Start date
2015-03-06
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: renal failure. Condition 2: CMV infection. Acute renal failure Other and unspecified infectious diseases

Interventions

Intervention 1: control group: treatment with Valganciclovir, 10-15 mg per kg for everyone, daily, for 3 months. Intervention 2: intervention group: treatment with valganciclovir, 10-15 mg per kg for
Treatment - Drugs
control group: treatment with Valganciclovir, 10-15 mg per kg for everyone, daily, for 3 months
intervention group: treatment with valganciclovir, 10-15 mg per kg for everyone, daily, for 6 months

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 14 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: The children who receive organs from people who are CMV positive; The children are 1-14 years-old Exclusion criteria: The use of Thymoglobuline drug; The children who are effected severely by side effects of valganciclovir drug; for example: severe leukopenia or anemia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
CMV infection. Timepoint: before intervention, 15 days after intervention, every month until 1 year after intervention. Method of measurement: Laboratory methods of Qualitit PCR and PP65.

Secondary

MeasureTime frame
Side effects of valganciclovir drug like: Anemia and Allergic hypersensitivity. Timepoint: every month after intervention until 1 year. Method of measurement: clinical presentation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNiloofar Khosravi

Ali-Asghar Hospital

niloofarkhosravi@rocketmail.com+98 21 2222 2041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026