The study of Date Palm Pollen effect on sperm parameters in infertile men

Evaluation of Date Palm Pollen on the expression of PRDX1 and PRDX6 antioxidant genes in infertile men

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015021221014N2

Enrollment

Registered

2015-12-29

Start date

2016-03-27

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertility. Azoospermia NOS Oligospermia NOS

Interventions

Intervention 1: In addition to standard treatment by a urologist, the case group received 400 mg / kg of Date palm pollen powder in gelatin capsules for 74 days. Intervention 2: Intervention Control:

L-Carnitine daily.

Eligibility

Sex/Gender

Male

Age

20 Years to 45 Years

Inclusion criteria

Inclusion criteria: Normal anatomy of the genital area Infertility due to oligo asthenospermia

Exclusion criteria

Exclusion criteria: The case with the following criteria were excluded from the study: history of genetic and systemic disorders. reproductive tract abnormality testicular trauma alcohol and substance abuse and fertility medications at least for six months before participation

Design outcomes

Primary

Measure	Time frame
Change in count, Motility and morphology of sperm. Timepoint: 74 days after intervention. Method of measurement: Semen analysis.;Change in PRDX1,PRDX6 antioxidant gene expression. Timepoint: 74 days after intervention. Method of measurement: evaluation of gene expression using Real time PCR Method.	—

Secondary

Measure	Time frame
Semen samples were obtained twice from the case group, before and after treatment, and once from the control group through masturbation, masturbation and abstinence for three to five days. We then collected fresh semen samples in sterile plastic containers. Timepoint: 74 days after consumption of Date Palm Pollen. Method of measurement: The samples were exposed to 37 ° C for 30 minutes for liquefaction and semen analysis (fluid volume, pH,viscosity, sperm morphology, concentration and motility) was performed immediately according to the WHO guideline. Sex hormones were also examined using ELISA. In addition, in this clinical trial, a blind and comparative semen analysis was performed by a technician blindly.	—

Measure

Time frame

Semen samples were obtained twice from the case group, before and after treatment, and once from the control group through masturbation, masturbation and abstinence for three to five days. We then collected fresh semen samples in sterile plastic containers. Timepoint: 74 days after consumption of Date Palm Pollen. Method of measurement: The samples were exposed to 37 ° C for 30 minutes for liquefaction and semen analysis (fluid volume, pH,viscosity, sperm morphology, concentration and motility) was performed immediately according to the WHO guideline. Sex hormones were also examined using ELISA. In addition, in this clinical trial, a blind and comparative semen analysis was performed by a technician blindly.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKianoosh malekzadeh

Bandare-abbas University of Medical Sciences

Keyanoosh@gmail.com+98 76 3333 7192

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026