effects of nasal lavage using solutions of hypertonic saline, isotonic saline and hypotonic saline in treating the symptoms of chronic sinusitis

A comparison between the effects of nasal lavage using solutions of hypertonic saline, isotonic saline and hypotonic saline in treating the symptoms of chronic sinusitis

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015021020320N2

Enrollment

185

Registered

2015-07-02

Start date

2014-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic sinusitis. Chronic sinusitis

Interventions

Intervention 1: Intervention group 1- medication as well as nasal lavage of hypertonic saline. Intervention 2: Intervention group 2-medication in addition to nasal lavage of isotonic saline. Intervent

Treatment - Drugs

Placebo

Intervention group 1- medication as well as nasal lavage of hypertonic saline

Intervention group 2-medication in addition to nasal lavage of isotonic saline

Intervention group 3- medication plus nasal lavage of hypotonic saline

Control goup - just medication recieve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: inclusion criteria: chronic sinusitis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Headache. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Discharge from the nose and throat. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Nasal obstruction. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Coughing. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Olfactory problems. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Feeling of fullness in the face. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).	—

Measure

Time frame

Headache. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Discharge from the nose and throat. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Nasal obstruction. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Coughing. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Olfactory problems. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).;Feeling of fullness in the face. Timepoint: before treatment and 3 months later. Method of measurement: lack of the effect (1 score), minor effect (2 scores), the relative effect (3 scores) or the full effect (4 scores).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Somaye Araghi

Jondishapour Ahvaz University of Medical Sciences

savesina@yahoo.com+98 61 3333 9664

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026