Multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Diagnosis of a neurologist Weakness in somatosensory function based on sensory evaluation EDSS score 2 to 5.5 (for the ability to perform or complete gait tests according to previous studies) The ability to walk a distance of 25 feet with or without assistive device Ability to stand independently for 2 minutes
Exclusion criteria
Exclusion criteria: The underlying illnesses (such as diabetes and epilepsy) or any problems with neuro-musculoskeletal system other than multiple sclerosis (eg, history of surgery, fracture) disrupts the balance and sensory status Receive corticosteroid treatment one month before the study Uncorrected visual disorders Exacerbation of symptoms Changes in medications during the study Attack 30 days before the start of the study or during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Static balance. Timepoint: Before the intervention, a week after the intervention. Method of measurement: Participants are asked to stand quiet on the force-plate while put the feet together and keep the arms relaxed beside the body. The center of pressure is recorded during 60 second of standing.;Dynamic balance. Timepoint: Before the intervention, a week after the intervention. Method of measurement: Timed up and go test: Participants sit on a chair to start the test They are asked to walk with maximum speed during test. They rise with a "go" signal and walk until reach a line at 3 meters distance from the chair then turn and walk back to the chair and sit on it. The time is recorded using a stopwatch.;Spatial-temporal parameters of gait. Timepoint: Before the intervention, a week after the intervention. Method of measurement: Walking of participant will be recorded using a motion capture system then parameters of the "gait symmetry" calculated and reported using a Visual 3D software.;Somatosensory(sense of joint position). Timepoint: Before the intervention, a week after the intervention. Method of measurement: Ankle proprioception was measured using perception of the inclination whilst participants stood over an adjustable slope box with closed eyes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fatigue. Timepoint: Before the intervention, a week after the intervention. Method of measurement: The level of fatigue will be measured using "Fatigue severity scale".;Pain. Timepoint: Before the intervention, a week after the intervention. Method of measurement: The participants' pain will be quantified using "Visual analog scale".;Spasticity. Timepoint: Before the intervention, a week after the intervention. Method of measurement: Muscle spasticity will be measured using "Modified Ashworth scale". | — |
Countries
Iran (Islamic Republic of)
Contacts
Esfahan University of Medical Sciences