Evaluation of intrauterine injection of recombinant human chorionic gonadotropin at different doses in improvement of pregnancy rates in in vitro fertilization/intracytoplasmic sperm injection

Evaluation the effect of intrauterine injection of recombinant human chorionic gonadotropin at different doses, before embryo transfer in improvement of implantation and pregnancy rates in in vitro fertilization/intracytoplasmic sperm injection: a prospective randomised controlled trial study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015020921008N1

Enrollment

420

Registered

2015-04-11

Start date

2015-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Female Infertility. Female Infertility

Interventions

Intervention 1: Intervention group: receiving rhCG as intrauterine injection 12 minutes before ET. . Intervention 2: Control group: undergoing ET without a previous intrauterine injection of rhCG.

Treatment - Drugs

Intervention group: receiving rhCG as intrauterine injection 12 minutes before ET. .

Control group: undergoing ET without a previous intrauterine injection of rhCG.

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria: female age under 40 years old with infertility. Exclusion criteria: previous IVF/ICSI trials, including a successful trial, endometriosis, azoospermia, uterine myoma or previous myomectomy, or the existence of hydrosalpinges.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Implantation rate. Timepoint: two weeks after embryo transfer. Method of measurement: conventional pregnancy test.	—

Secondary

Measure	Time frame
Clinical pregnancy rate. Timepoint: three weeks after a positive pregnancy test. Method of measurement: ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactdr Gooya Madadi

Shiraz University of Medical Sciences

gmadadi@sums.ac.irs.kharati@yahoo.com+98 71 3227 9715

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026