The effect of prophylactic administration of intravenous Ondansetron for control of shivering during and after spinal anesthesia for cesarean section

Effect of Ondansetrone for prevention of shivering during and after cesarean with spinal anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015020911700N6

Enrollment

100

Registered

2015-06-29

Start date

2015-03-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Intra and post spinal anesthesia shivering. Condition 2: complications of anaesthesia. Hypothermia, not associated with low environmental temperature Other complications of anaesthesia

Interventions

Intervention 1: Intervention:In this group ondansetron 4 mg iv and total volume of 2 ml was administered after neonatal delivery and clamping of the cord for prevention of intra and post-operative shi

Prevention

Intervention:In this group ondansetron 4 mg iv and total volume of 2 ml was administered after neonatal delivery and clamping of the cord for prevention of intra and post-operative shivering .

control group:In this group normal saline iv in total volume of 2 ml was administered as placebo after neonatal delivery and clamping of the cord .

Eligibility

Sex/Gender

Female

Age

18 Years to 44 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria:Pregnant women candidate for elective cesarean section with spinal anesthesia; ASA physical class I or II with informed consent for spinal anesthesia Exclusion criteria:Patients with ASA physical class III or higher;preexisting cardiovascular diseases; respiratory diseases; preeclampsia or any hypetensive disorders during pregnancy;fever; any contraindication for performing spinal anesthesia

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Incidence of intra and postoperative shivering. Timepoint: during surgery and in recovery. Method of measurement: Observation.;Severity of intra and postoperative shivering. Timepoint: during surgery and in recovery. Method of measurement: Crossly and Mahjon five-point scoring system.	—

Secondary

Measure	Time frame
Need for rescue tyreatment of shivering. Timepoint: during surgery and in recovery. Method of measurement: observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz Moslemi

Research Center,Tabtiz University Of Medical Sciences

moslemifa@gmail.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026