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Compare of drug therapy with cognitive behavioral therapy in improvement of enuresis in children

Compare of drug therapy (with oxibutinin, imipramine and desmopressin)with cognitive behavioral therapy to improve the rate of primary nocturnal enuresis in new school -aged children of education and training organization, referred to specialized clinics in 2014-2015

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201502091061N22
Enrollment
45
Registered
2015-04-20
Start date
2015-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary enuresis. Nonorganic enuresis

Interventions

Intervention 1: imipramine tablet (50mg)before sleep for one month, oxibutinin tablet (5mg)two times a day for one month, desmopressin spray (20micro g)intra nasal before sleep for one month. Interve
Treatment - Drugs
Behavior
imipramine tablet (50mg)before sleep for one month, oxibutinin tablet (5mg)two times a day for one month, desmopressin spray (20micro g)intra nasal before sleep for one month
cognitive behavioral therapy by using of less drinking before sleep, alarm clock wakes at night, enuresis alarm, hypnosis, trying to remember to keep dry, parents wakes at night, punishment for wet ni

Sponsors

Rafsanjan University of Medical Siences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
7 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion :to have primary nocturnal enuresis and being 7to 12 years old , exclusion :to have neurogenic bladder, central nervous system disorders and secondary nocturnal enuresis

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Number of nocturnal enuresis. Timepoint: before the intervention. Method of measurement: olness questionnaire of nocturnal enuresis.

Secondary

MeasureTime frame
Response to drug therapy (oxibutinin, imipramine and desmopressin). Timepoint: one, two, three and four months after the start of study. Method of measurement: olness questionnaire of nocturnal enuresis.;Response to cognitive behavioral therapy. Timepoint: one, two, three and four months after the start of intervention. Method of measurement: olness questionnaire of nocturnal enuresis.

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026