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Effect of mixed of garlic and lemon juice on hyperlipidemia

Effect of garlic and lemon juice mixture on lipid profile and some cardiovascular risk factors in people 30-60 years old with hyperlipidemia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015020720986N1
Enrollment
120
Registered
2015-03-07
Start date
2013-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperlipidemia. Disorders of lipoprotein metabolism and other lipidaemias

Interventions

Intervention 1: first group received 20 grams of garlic plus 1 tablespoon lemon juice daily. Intervention 2: forth group did not recive garlic and lemon juice during the intervention. Intervention 3
Prevention
first group received 20 grams of garlic plus 1 tablespoon lemon juice daily
forth group did not recive garlic and lemon juice during the intervention
second group recived 20 gram of garlic, daily
third group recived 1 tablespoon of lemon juice, daily

Sponsors

Vice chancellor for research, Isfahan University of Medical Science
Lead Sponsor
Isfahan University of Medical Sciences, School of Nutrition-School Nutrition Research Center
Collaborator

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Subjects were eligible if they have a total cholesterol and LDL levels between 240-200 mmol/l and 160-100 mmol/l respectively. People should not be suffering from any other diseases, including heart problems, kidney, lung, thyroid disorders, gastrointestinal, rheumatoid arthritis and other liver problems such as hepatitis or fatty liver, pregnancy or lactating, no smoking, their weight may not change fast in the last two months, should not use drugs that affect blood sugar, blood fat, blood pressure and anti-inflammatory and not to have any sensitivity to garlic and lemon juice. Individual with a history of chronic disease, consuming medicine and flowing special regimen were excluded.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Total cholesterol. Timepoint: in the first of intervention and end of 8th week. Method of measurement: enzymatic, mg/dl.;Serum low-density lipoprotein cholesterol (LDL-C) levels. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Enzymatic, mg/dl.;Serum hight-density lipoprotein cholesterol (HDL-C) levels. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Enzymatic, mg/dl.;Triglyceride. Timepoint: in the first of intervention and end of 8th week. Method of measurement: Enzyme colorimetric methods, mg/dl.;Fibrinogen. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Clauss method.;Systolic blood pressure. Timepoint: Before intervention and at the end of 8th week. Method of measurement: mmHg, Mercurial sphygmomanometer.;Diastolic blood pressure. Timepoint: Before intervention and at the end of 8th week. Method of measurement: mmHg, Mercurial sphygmomanometer.;Body mass index. Timepoint: Before intervention and at the end of 8th week. Method of measurement: kg/m2, Weight/Height squar.;Fasting blood sugar. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Enzymatic, mg/dl.;Weight. Timepoint: Before intervention and at the end of 8th week. Method of measurement: Scale, kilogram.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegar Aslani

Isfahan University of Medical Sciences

negar_aslani@nutr.mui.ac.ir; negaraslani5@yahoo.com+98 31 3433 2929

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026