Type 2 diabetes. Type 2 diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group: date seed powder. This group will consume two sachets of 2.5 g of date seed powder (Flavinea Company, Iran) daily for 2 months in the morning and evening in food su
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 50 Years
Inclusion criteria
Inclusion criteria: Have at least 6 months of diabetes history No weight changes during the last 3 months No insulin therapy Use of blood sugar lowering drugs Tendency to consume palm kernel powder during the study Having a BMI between 25 and 35
Exclusion criteria
Exclusion criteria: Use of glucocorticoids, laxatives, anti-obesity, multivitamins, nonsteroidal anti-inflammatory drugs (NSAIDS) and antibiotics Take antioxidant supplements at least three months before the start of the study History of weight loss diet in the last 6 months or special diet Having diseases such as intestinal diseases such as inflammation of the intestines, intestinal cancer and digestive problems Having thyroid disorders, heart disease, kidney, liver, lung, infectious and other cancers treated with radiotherapy Alcohol or smoking Pregnancy, breastfeeding, being an athlete or doing strenuous physical activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lipid profile (TG, TC, HDL-c). Timepoint: At baseline and and two months after the start of the study. Method of measurement: Kit.;Total antioxidant capacity. Timepoint: At baseline and two months after start of the study. Method of measurement: Kit.;Malondialdehyde. Timepoint: At baseline and two months after start of the study. Method of measurement: kit.;Tumor Necrosis Factor(TNF). Timepoint: At baseline and two months after start of the study. Method of measurement: kit.;Highly sensitive C-reactive protein(hs-CRP ). Timepoint: At baseline and two months after start of the study. Method of measurement: kit.;HbA1c. Timepoint: At baseline and two months after start of the study. Method of measurement: kit.;Fasting glucose. Timepoint: At baseline and two months after start of the study. Method of measurement: kit.;Fasting insulin. Timepoint: At baseline and two months after start of the study. Method of measurement: kit.;Interleukins 4, 6, 10, 18. Timepoint: At baseline and two months after start of the study. Method of measurement: enzyme-linked immunosorbent assay (ELISA) kit.;Fructosamine. Timepoint: At baseline and two months after start of the study. Method of measurement: enzyme-linked immunosorbent assay (ELISA) kit.;LPS endotoxin. Timepoint: At baseline and two months after start of the study. Method of measurement: enzyme-linked immunosorbent assay (ELISA) kit.;Pentosidine. Timepoint: At baseline and two months after start of the study. Method of measurement: enzyme-linked immunosorbent assay (ELISA) kit.;Total oxidant status (TOS). Timepoint: At baseline and two months after start of the study. Method of measurement: kit.;Carboxymethyl lysine (CML). Timepoint: At baseline and two months after start of the study. Method of measurement: enzyme-linked immunosorbent assay (ELISA) kit.;Soluble receptor for advanced glycation end-products. Timepoint: At baseline and two months after start of the study. Method of measurement: enzyme-linked immunosorbent assay (EL | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Mass Index (BMI). Timepoint: At baseline and two months after baseline. Method of measurement: Scale-Meter.;Energy intake, Daily macronutrient intake (carbohydrate, protein, fat). Timepoint: At baseline and two months after baseline. Method of measurement: questionnaire.;General Health , Sleep quality, Depression, Anxiety and Stress. Timepoint: At baseline and two months after baseline. Method of measurement: questionnaire.;Blood pressure. Timepoint: At baseline and two months after baseline. Method of measurement: manometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParvin Dehghan
Tabriz University of Medical Sciences
Outcome results
None listed