Priority of Quince Seed Cream in the Healing of Skin Ulcers

Priority of 5% Quince Seed Cream Versus 1% Phenytoin Cream in the Healing of Skin Ulcers

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015020414190N7

Enrollment

Registered

2015-09-16

Start date

2012-09-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgical Site Infection and Wound Healing. Local infection of skin and subcutaneous tissue, unspecified

Interventions

Intervention 1: Intervention group: received 5% quince seed cream. It was prepared in the department of pharmacology and toxicology at Ahvaz Jundishapur University of Medical Sciences. Patients were a

Treatment - Drugs

Intervention group: received 5% quince seed cream. It was prepared in the department of pharmacology and toxicology at Ahvaz Jundishapur University of Medical Sciences. Patients were asked to apply th

Control group: received 1% phenytoin cream (Abidi pharmaceutical laboratory, Tehran, Iran). All patients were asked to apply the creams to their ulcers, twice per day.

Eligibility

Sex/Gender

All

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: patients referred with skin ulcer, caused by punch biopsy; age between 18 to 40 years old. Exclusion criteria: diseases affecting wound healing (diabetes, kidney disease, anemia, liver diseases, anxiety disorders); smoking and drug abuse; consumption of drugs affecting wound healing (glucocorticoids, anti-coagulation, immune system suppressants, antibiotics or chemotherapy agents).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Size of the ulcer. Timepoint: Healing of ulcers was evaluated before and during the study (on the 3rd, 7th, and 14th days), with respect to the size of the ulcer. Method of measurement: We used a calibrated transparent paper to record the exact surface area, then scanned for evaluation using computerized planimetry digital image processing software (Florida, USA) to calculate the exact size of ulcers.	—

Measure

Time frame

Size of the ulcer. Timepoint: Healing of ulcers was evaluated before and during the study (on the 3rd, 7th, and 14th days), with respect to the size of the ulcer. Method of measurement: We used a calibrated transparent paper to record the exact surface area, then scanned for evaluation using computerized planimetry digital image processing software (Florida, USA) to calculate the exact size of ulcers.

—

Secondary

Measure	Time frame
Wound infection. Timepoint: At the end of the study. Method of measurement: Clinical findings and wound culture.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamideh Farajzadeh

Ahvaz Jundishapur University of Medical Sciences

farajzadeh.H@ajums.ac.ir+98 61 3333 6754

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026