Antioxidant role of palm pollen in infertility

Evaluation of the Antioxidant Role of Palm Pollen in Oligospermic and Asthenozoospermic Men and Its Correlation with Count, Motility and Morphology of the Sperm

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015020120895N2

Enrollment

120

Registered

2015-10-12

Start date

2016-03-21

Completion date

Unknown

Last updated

2021-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertility. Azoospermia NOS Oligospermia NOS

Interventions

In addition to standard treatment by a urologist, the case group received 400 mg / kg of palm pollen powder in gelatin capsules for two months..

Eligibility

Sex/Gender

Male

Age

20 Years to 42 Years

Inclusion criteria

Inclusion criteria: Normal anatomy of the genital area; Infertility due to oligo asthenospermia

Exclusion criteria

Exclusion criteria: The case with the following criteria were excluded from the study: history of genetic and systemic disorders, reproductive tract abnormality, testicular trauma, alcohol and substance abuse, and fertility medications at least for six months before participation.

Design outcomes

Primary

Measure	Time frame
Evaluation of count, motility and morphology of sperm. Timepoint: 2 months. Method of measurement: Semen analysis.;Evaluation of expression of antioxidant SOD, CAT, GPX, NRF2 and KEAP1 genes. Timepoint: 2 months. Method of measurement: RT-PCR.	—

Secondary

Measure	Time frame
Semen samples were obtained twice from the case group, before and after treatment, and once from the control group through masturbation, masturbation and abstinence for three to five days. We then collected fresh semen samples in sterile plastic containers. Timepoint: 2 months after consumption of palm pollen. Method of measurement: The samples were exposed to 37 ° C for 30 minutes for liquefaction and semen analysis (fluid volume, pH, viscosity, sperm morphology, concentration and motility) was performed immediately according to the WHO guideline. Sex hormones were also examined using ELISA. In addition, in this clinical trial, a blind and comparative semen analysis was performed by a technician blindly.;Measurement of antioxidant genes and 8- isoprene index. Timepoint: After two months, receive palm pollen. Method of measurement: BSA-free Ham’s-F10 was used twice to wash the samples and then stored in RNALater solution (Qiagen: Germany) at -80 ° C until RNA extraction. Then, after extraction and PCR test, real-time test was performed on the samples.	—

Measure

Time frame

Semen samples were obtained twice from the case group, before and after treatment, and once from the control group through masturbation, masturbation and abstinence for three to five days. We then collected fresh semen samples in sterile plastic containers. Timepoint: 2 months after consumption of palm pollen. Method of measurement: The samples were exposed to 37 ° C for 30 minutes for liquefaction and semen analysis (fluid volume, pH, viscosity, sperm morphology, concentration and motility) was performed immediately according to the WHO guideline. Sex hormones were also examined using ELISA. In addition, in this clinical trial, a blind and comparative semen analysis was performed by a technician blindly.;Measurement of antioxidant genes and 8- isoprene index. Timepoint: After two months, receive palm pollen. Method of measurement: BSA-free Ham’s-F10 was used twice to wash the samples and then stored in RNALater solution (Qiagen: Germany) at -80 ° C until RNA extraction. Then, after extraction and PCR test, real-time test was performed on the samples.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Soghra Fallahi

fertility and infertility Research Center of Shahid Mohammadi Hospital, Bandar Abbas, Iran

fallahi.leila@gmail.com+98 76 3333 7192

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026