NEC. Necrotizing enterocolitis of fetus and newborn
Conditions
Interventions
Intervention 1: In the lactulose given group after consideration the inclusion and exclusion criteria for premature infant <1500gr that their milk begin lactulose 1%added and it continued on till the
Treatment - Drugs
Placebo
In the lactulose given group after consideration the inclusion and exclusion criteria for premature infant <1500gr that their milk begin lactulose 1%added and it continued on till the milk volume 150
In the control group after consideration the inclusion and exclusion criteria for premature infant<1500 gr that their milk begin water injectin added and it cntinues to till the milk volume to 150 cc
Sponsors
Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 30 Days
Inclusion criteria
Inclusion criteria: Inclusion criteria: prematurity; birth weight equal and lower than 1500 gr; at the time of beginning milk. Exclusion criteria: major congenital anomalies; asphyxia; GI anomalies; congenital cyanotic heart disease.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GI microbial changes. Timepoint: 30 days. Method of measurement: Stool exam.;NEC. Timepoint: 30 days. Method of measurement: Patient examination and observation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospital stay. Timepoint: 30 days. Method of measurement: Daily recorded sheets.;Death. Timepoint: During hospital stay. Method of measurement: Daily recorded sheets.;Being NPO. Timepoint: 30 days. Method of measurement: Daily recorded sheets.;Milk intolerance. Timepoint: 30 days. Method of measurement: Daily recorded sheets.;Time of becoming full volume. Timepoint: 30 days. Method of measurement: Daily recorded sheets. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Elahe Shirani
Isfahan University of Medical Sciences
Outcome results
None listed