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A Comparative effect of fentanyl and meperidine added to 8 mg bupivacaine for spinal anesthesia in elective cesarean section surgery

A Comparative effect of fentanyl and meperidine added to 8 mg bupivacaine for spinal anesthesia in elective cesarean section surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015013119470N14
Enrollment
120
Registered
2015-02-09
Start date
2013-04-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cesarean. Delivery by elective caesarean section

Interventions

Intervention 1: Group1 : bupivacaine 0.5% (8mg), 15 micrograms fentanyl and 0.1 ml normal saline total volume 2ml. Intervention 2: Group2 :intrathecal bupivacaine 0.5% (8mg), 15 mg of meperidine and 0
Treatment - Drugs
Group1 : bupivacaine 0.5% (8mg), 15 micrograms fentanyl and 0.1 ml normal saline total volume 2ml.
Group2 :intrathecal bupivacaine 0.5% (8mg), 15 mg of meperidine and 0.1 ml normal saline total volume 2ml.
Group3:intrathecal bupivacaine 0.5% (10 mg) (total volume 2 ml)

Sponsors

Vice Chancellor for Research; Shiraz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: pregnant women, ASA I-II with singleton pregnancies who were underwent elective Caesarean section, Exclusion criteria: Patients with cardiovascular disorders, renal failure, coagulopathy, sensitivity to the drugs, preeclampsia, lack of consent and spinal anesthesia contraindication, history of seizures or other neurological diseases, (IUGR).

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

MeasureTime frame
To determine the duration of sensory block in patients receiving intrathecal meperidine with bupivacaine 0.5%. Timepoint: Prioperative and post operative. Method of measurement: Pinprick Scale.

Primary

MeasureTime frame
Determine the duration of sensory block in patients with intrathecal fentanyl added to bupivacaine 0.5%. Timepoint: Perioperative and Post-operative. Method of measurement: Pinprick.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAzadeh Azizolahi

Shiraz University of Medical Sciences

azadehazizollahi@gmail.com+98 71 3647 4270

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026