ischemic brain stroke. Cerebral infarction
Conditions
Interventions
Intervention 1: intervention group : 1 melatonin tablet (3mg) every night for 2 months.
all patients will receive standard treatment of stroke(Plavix tablet 75mg /daily). Intervention 2: patients
Treatment - Drugs
intervention group : 1 melatonin tablet (3mg) every night for 2 months.
all patients will receive standard treatment of stroke(Plavix tablet 75mg /daily)
patients whom randomized to placebo group will received placebo tablets during 8 weeks of clinical trial course
Sponsors
Arak University of Medical Sciences , Office of Vice Chancellor for Research
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: inclusion criteria : Patients admitted in Valiasr Hospital of Arak city with acute ischemic stroke approved by a neurologist and imaging that caused hemiparesis or hemiplegia ; Those who aged between 18 years and 85 years exclusion criteria : severe post-stroke disability (National Institutes of Health stroke scale [NIHSS] score >20) ; substantial pre-morbid disability ; or a pre-existing deficit that could interfere with assessments— ie residual motor deficit from a previous stroke ; pregnancy and other major diseases that would prevent follow-up
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of stroke. Timepoint: baseline and after 2 months. Method of measurement: Canadian Neurological Scale of Stroke (CNSS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShayan Amjadi
Students Research Committe , Medicine faculty , Arak University of Medical Sciences
Outcome results
None listed