Pain control after coronary artery bypass grafting surgery (CABG)

Comparison of the use of morphine bolus and using a portable infusion pumps for pain management in patients after coronary artery bypass grafting surgery (CABG)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015012814359N3

Enrollment

Registered

2015-04-24

Start date

2015-04-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease. Atherosclerotic heart disease

Interventions

Intervention 1: Intervention 1: Infusion 30 mg morphine sulfate 10 mg/cc with speed of 0.02 mg/kg/h using PCA pump up to 24 hours. Intervention 2: Intervention 2: Injection 0.03 mg/kg bolus morphine

Treatment - Drugs

Intervention 1: Infusion 30 mg morphine sulfate 10 mg/cc with speed of 0.02 mg/kg/h using PCA pump up to 24 hours

Intervention 2: Injection 0.03 mg/kg bolus morphine sulfate 10 mg/cc three time in one hour up to 24 hours

Eligibility

Sex/Gender

All

Age

30 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients aged 30-65 years;Three vessels disease (3VD) Exclusion criteria:Patients not extubated after 8 hours;Patients requiring reoperation for bleeding ;Patients with advanced heart failure (requiring high-dose postoperative inotropic or need to put intra-aortic balloon pump (IABP)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Every 2 hours for 12 hours and then every 4 hours to 24 hours. Method of measurement: Using verbal pain score (VPS).0-10.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVali Imantalab

Guilan University of Medical Sciences

aecguilan1392@gmail.com+98 13 3366 3070

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026