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The effect of folic acid on sexual function in postmenopausal women

The effect of folic acid on sexual function in postmenopausal women

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150128020854N8
Enrollment
100
Registered
2020-08-02
Start date
2020-08-10
Completion date
Unknown
Last updated
2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sexual function.

Interventions

Intervention 1: Intervention group: oral folic acid tablets, 5 mg, 1 tablet daily for 8 weeks constructed by Rouz Darou factory. Intervention 2: Control group: placebo tablets, 1 tablet daily, for 8

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Being Iranian Lack of speech, hearing or mental disorders that prevent communication with the researcher It's been at least a year since they stopped menstruating Being in the first ten years of menopause being sexually active Lack of folic acid deficiency (self-report) Lack of any type of anemia (based on lab test) Not taking hormone replacement therapy Not using any chemical or herbal medicines (Gensing, Vitagnos, Maca, Femaxite capsules, Flibanserin) that affect sexual function (according to the woman) Lack of sexual problems in their spouses (such as erectile dysfunction or premature ejaculation, according to the self-report) No history of hysterectomy and oformorectomy, cystosel, rectosell, and mastectomy Lack of known mental illness in women and their spouses according to the self-report Any addicted to cigarettes, alcohol or drugs in women and their spouses Any history of known chronic diseases such as high blood pressure, diabetes, hyperlipidemia, asthma, weakening of the immune system, etc., according to the medical record Any specific incident or crisis in their life such as death or incurable disease in family members, change of residency and loss of job since 6 months ago Not using herbal teas while taking the medicine Not using anti convulsants Not being depressed, anxious or stressed (based on the results of the DOS questionnaire) Menopause occurs naturally (not followed by ovarectomy) Premature menopause does not occur Not having body mass index above 30

Exclusion criteria

Exclusion criteria: Possible sensitivity to folic acid

Design outcomes

Primary

MeasureTime frame
The outcome variable is the sexual function, which contains the body reacts at different stages of the sexual response cycle and will be measured by the Women's Sexual Function Index Questionnaire. Timepoint: At the beginning of the study (before the intervention), 4 and 8 weeks after the intervention. Method of measurement: The outcome measure variable will be evaluated with theFemale Sexual Function Index which is an indicator for women's sexual function. This questionnaire contains 19 questions and measures sexual function in 6 independent areas of sexual desire, sexual arousal (psychological stimulation), vaginal moisturizing, orgasm, satisfaction and sexual pain. The total score range is between minimum of 2 and a maximum of 36, and a higher score indicates a more desirable sexual function.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahnaz Asadi

Shahid Beheshti University of Medical Sciences

Mahnaz.asadii1992@gmail.com+98 21 8865 5366

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 9, 2026