Condition 1: postmenopausal women’s sexual function. Condition 2: severity of menopausal symptoms.
Conditions
Interventions
Intervention 1: Intervention group: oral magnesium tablets, each tablet contains 250 mg magnesium oxide, 2 tablets daily (one in the morning after breakfast and one at night after dinner), for 4 week
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Being Iranian. At least they should be able to read and write. Lack of speech, hearing or mental disorders that prevent communication with the researcher. At least one year has passed since the last menstruation. Being in the first five years of menopause. Have sexual activity in the last 6 months. Do not have magnesium deficiency (based on lab test). Do not use hormone replacement therapy. Do not use any chemical or herbal drug (ginseng, vitagenus, maca, femexite capsule, flibanserin) effective on sexual function (according to the self-report). Do not use any chemical or herbal drug to reduce the severity of menopausal symptoms (hot flashes, sleep disorders, etc.) (according to the self-report). Not using complementary and alternative medicine to reduce the severity of menopausal symptoms (yoga, acupuncture or other methods). Do not use multivitamins or minerals. Do not have diseases that affect sexual function (such as musculoskeletal diseases, multiple sclerosis, endometriosis, diabetes, hypertension) according to the self-report. Their spouses do not suffer from sexual problems (such as erectile dysfunction or premature ejaculation according to the self-report). Have not undergone hysterectomy and oophorectomy, cystocele and rectocele, and mastectomy. Lack of known mental illness in women and their spouses according to the self-report. Lack of addiction to cigarettes, alcohol or drugs. Do not have dietary restrictions. Do not suffer from kidney diseases, chronic diarrhea and diseases that lead to malabsorption (celiac, Crohn's disease, etc.) (according to the self-report). Lack of specific event or incident that represents a crisis in their life, such as death or incurable illness of family members, change of residence, loss of job since 6 months ago and marital infidelity, and not being on the verge of divorce. Menopause occurs naturally (not followed by oophorectomy). Premature menopause does not occurred. Have no marital conflicts. Obtaining a score of 5 or higher from the MRS questionnaire.
Exclusion criteria
Exclusion criteria: Use of corticosteroids, furosemide, hydrochlorothiazide, pantoprazole, omeprazole, drugs to prevent organ transplant rejection, and amphotericin B during the study. Failure to take medication regularly (if less than 51 tablets (that is less than 90% of all tablets) are taken). Unwillingness to continue participating in the study. Interruption of sexual activity during the study for any reason (such as illness, death of spouse, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sexual function. Timepoint: Before the intervention and immediately after the intervention. Method of measurement: Female sexual function index.;Severity of menopausal symptoms. Timepoint: Before the intervention and immediately after the intervention. Method of measurement: Menopause rating scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Aghahossein Shirazi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed