infertility. Complication associated with artificial fertilization, unspecified
Conditions
Interventions
Intervention 1: in intervention group 5 mmol/ml calcium ionophore in medium culture, immediately after ICSI, for 5 minutes and then washed at least 5 time by mops solution. Intervention 2: In control
Treatment - Drugs
in intervention group 5 mmol/ml calcium ionophore in medium culture, immediately after ICSI, for 5 minutes and then washed at least 5 time by mops solution.
In control group usual Intracytoplasmic sperm injection will be performed
Sponsors
Vice Chancellor for research of Shahid Sadoughi University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: patients with history of fertilization less than 50% in previous micro injection cycle, who are candidate for Intracytoplasmic sperm injection and morphology of sperm is normal. Exclusion criteria:women older than 40 years; women with FSH higher than 12; history of endocrine disorder
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fertilization rat. Timepoint: 16-18 hour. Method of measurement: Observation with microscope. | — |
Secondary
| Measure | Time frame |
|---|---|
| Chemical pregnancy. Timepoint: 14 days after embryo transfer. Method of measurement: serum ßhCG.;Clinical pregnancy. Timepoint: 3 weeks after positive serum ßhCG. Method of measurement: vaginal ultrosonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Eftekhar
Sadoughi University of Medical Science ,Yazd
Outcome results
None listed