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Herbal extract solution in treatment of seborrheic dermatitis

Evaluation of the effect and safety of herbal extracts anti dandruff formulation comparing with clotrimazole lotion in patients with seborrheic dermatitis referring to the clinic of center for research and training in skin diseases and leprosy during the year 1394

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015012520802N1
Enrollment
20
Registered
2015-08-15
Start date
2015-08-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seborrheic Dermatitis. Other seborrhoeic dermatitis

Interventions

Intervention 1: Volunteers in the intervention group use the anti dandruff lotion with herbal extracts twice a day for 4 weeks,1 cc per consumption topical on their scalp. Intervention 2: Volunteers i
Treatment - Drugs
Volunteers in the intervention group use the anti dandruff lotion with herbal extracts twice a day for 4 weeks,1 cc per consumption topical on their scalp
Volunteers in the control group use clotrimazole lotion 1 cc twice daily for 4 weeks, topically on their scalp

Sponsors

Vice chancellor for research,Islamic Azad University Pharmaceutical Branch of Tehran
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: male patients; healthy general condition; clinically diagnosed seborrheic dermatitis; 20-30 years old; consent form signed by patients. Exclusion criteria: use of topical steroids during 2 weeks ago; use of topical retinoids during 2 weeks ago; use of topical antifungals during 2 weeks ago; use oftopical anti-inflammatory druds during 2 weeks ago; use of topical antibiotics and any other topical treatments for seborrheic dermatitis like anti-dandruff shampoo and coal tar during 2 weeks ago; use of systemic anti-fungals during the last month; use of systemic steroids during the last month; use of systemic antibiotic during the last month; use of systemic anti-inflammatory drugs and immunomodulator drugs during the last month; use oral retinoid during last 6 months; history of hypersensitivity to azoles or herbal compound of our solution; comorbidities(AIDS,Parkinson,diabetes,…); skin disease like psoriasis, acne, …

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Scalp sebum. Timepoint: Beginning of the study, 2 weeks and 4 weeks after starting the treatment. Method of measurement: Sebometer.;Scalp PH. Timepoint: Beginning of the study, 2 weeks and 4 weeks after starting the treatment. Method of measurement: PH meter.;Dandruff. Timepoint: Beginning of the study, 2 weeks and 4 weeks after starting the treatment. Method of measurement: Pixel.

Secondary

MeasureTime frame
Erythema and itching. Timepoint: Begining of the study,2 weeks and 4 weeks after treatment. Method of measurement: Clinical examination, Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hamid Reza Ahmadi Ashtiani

Pharmaceutical Sciences Branch of Islamic Azad University

ahmadi@iaups.ac.ir+98 21 2264 0051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026