Effect of Premedication with dexmedetomidin and ketamin in Severity of Pain after Infusion of Propofol.

Comparing the efficacy of dexmedetomidin and ketamin infusion in reducing pain following preoperative propofol injection

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150125020795N8

Enrollment

100

Registered

2019-12-05

Start date

2019-10-15

Completion date

Unknown

Last updated

2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post Injectional Pain of Propofol. Other complications of anesthesia

Interventions

Intervention 1: intervention group will receive 0.5 mg/kg dexmedetomidin diluted in 20cc normal saline within 10 minutes intravenously. Intervention 2: control group will receive 0.5 mg/kg ketamin dil

Eligibility

Sex/Gender

All

Age

15 Years to 65 Years

Inclusion criteria

Inclusion criteria: All of Patients who Being a Candidate for Elective Surgery and Based on ASA Classification are 1 or 2 ASA Class

Exclusion criteria

Exclusion criteria: Patients with Cardiovascular, Hepatic and Kidney Disease. Need for Rapid Sequence Induction of Anesthesia. Patients with Psychiatric Disorders. Patients under Prescription of Sedative Drugs in the last 24 hours.

Design outcomes

Primary

Measure	Time frame
Post injectional pain of propofol. Timepoint: Amount of pain evaluate on 5, 10, 15 and 20 seconds after injection of propofol. Method of measurement: Four Numerical Verbal Rating Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamad Eslam Jamal Golzari

Tabriz University of Medical Sciences

golzaris@tbzmed.ac.ir+98 41 3334 1994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026