Condition 1: Postoperative nausea and vomiting. Condition 2: Postoperative pain. Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure Other complications of anesthesia
Conditions
Interventions
Intervention 1: Intervention group: Group 1, will recieve 3 mg IV granisetron before induction of anesthesia. Intervention 2: Control group: Group 1, will recieve50 mg IV diphenhydramine before induc
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 59 Years
Inclusion criteria
Inclusion criteria: All of Patients at age of 18 to 59 who Being a Candidate for Elective Surgery and Based on ASA Classification are 1 or 2 ASA Class.
Exclusion criteria
Exclusion criteria: Patients under Prescription of anti-nausea Drugs in the last 24 hours. Patients with Cardiovascular, Hepatic , Kidney ,blood pressure and hyperadiposis Disease pregnant women and during menstruation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of postoperative nausea and vomiting. Timepoint: Recovery and at 3, 6, and 24 h postoperatively. Method of measurement: scoring by (0=non, 1=nausea, 2=vomiting, 3=vomiting >2 times). | — |
Secondary
| Measure | Time frame |
|---|---|
| Severity of pain after injection of diphenhydramine and granisetron. Timepoint: Amount of pain evaluate on 5, 10, 15 and 20 seconds after injection of diphenhydramine and granisetron. Method of measurement: Four Numerical Verbal Rating Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamad Eslam Jamal Golzari
Tabriz University of Medical Sciences
Outcome results
None listed