Cutaneous Leishmaniasis. Protozoal diseases
Conditions
Interventions
intervention: Injection of interferon gamma with standard treatment (Injection of Glucantime).
control: Glucantime standard drug..
Treatment - Drugs
intervention: Injection of interferon gamma with standard treatment (Injection of Glucantime).
control: Glucantime standard drug.
Sponsors
Mashhad University of Medical Sciences, Vice Chancellor for Research
Eligibility
Sex/Gender
All
Age
18 Years to 139 Years
Inclusion criteria
Inclusion criteria: Inclusion criterias: Positive smear or biopsy of the lesion in terms of Amastigotes; Not sensitivity to glucantime; The patient who has indications of topical treatment based on state protocol; Less than one year past from onset of the illness; No treatment is received in at least 2 months; Not pregnant and not lactating; The patient is willing to participate in the study. exclusion criterias: No have regular visit; Secondary infection of the lesion based on clinical features and judging therapist; Use of other medications during the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of healing. Timepoint: Once a week up to 12 weeks after treatment. Method of measurement: Outcomes based on the percent reduction of induration: full healing (100% healing), significant healing (75%> reduce induration), relatively healing (50-75% reduce induration), low healing (25-50% reduce induration), no response (25%< reduce induration). | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment effects. Timepoint: Once a week up to 12 weeks after treatment. Method of measurement: Local or systemic clinical reactions cause of using drugs. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFakhrozaman Pezeshkpoor
Mashhad University of Medical Sciences
Outcome results
None listed