Pain after cesarian section. Delivery by cesarean section, unspecified
Conditions
Interventions
Intervention 1: Before starting surgery patients in group A (acetaminophen) will receive a suppository placebo an then two other doses, all 8 hr apart. At the end of the procedure a 0.6 ml/kg normal s
Treatment - Drugs
Before starting surgery patients in group B (diclofenac + bupivacaine) will receive a suppository diclofenac (50 mg) an then two other doses, all 8 hr apart. At the end of the procedure 1.5 mg/kg bupi
Before starting surgery patients in group A (acetaminophen) will receive a suppository placebo an then two other doses, all 8 hr apart. At the end of the procedure a 0.6 ml/kg normal saline (as placeb
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: full-term pregnant women candidate for elective cesarean section; age: 18 to 45 years;ASA class1 and 2; between 50 to 80kg weight Exclusion criteria : strong indication for spinal anesthesia; emergency cesarean section; opioid addiction; anxiety and depressive disorders; gastro-esophageal reflux disease; severe renal disease; heart disease liver disease; seizure disease; positive history of hypersensitivity to the drugs used in the study; analgesic consumption in the last 24 hr; non-cooperative patients
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Every 6 hr in the first 24 hr after cesarian section. Method of measurement: NRS score. | — |
Secondary
| Measure | Time frame |
|---|---|
| 24 hr morphine consumption. Timepoint: Once, 24 hr after operation. Method of measurement: Total dose of morphine administered (mg).;Time to first request for analgesic after operation. Timepoint: Once after the procedure. Method of measurement: Time interval from the end of the surgery to the first patient's request for analgesic (minute).;Patient's sleep. Timepoint: Next morning after operation. Method of measurement: 3 point scale: 1: good - 2: interrupted - 3: no sleep.;Sedation score. Timepoint: Every 6 hr after operation till 24 hr. Method of measurement: Wilson scale.;Pain intensity at ambulation. Timepoint: Once during ambulation. Method of measurement: NRS.;Drug side effects: nausea and vomiting. Timepoint: Every 6 hr after operation till 24 hr. Method of measurement: 3 points scale: 1: non, 2: nausea, 3: nausea and vomiting.;Patients satisfaction of pain control. Timepoint: Once, 24 hr after operation. Method of measurement: 11 points NRS (0: extremely dissatisfied, 5: neutral, and 10: most satisfied).;Drug side effects: pruritus. Timepoint: Every 6 hr till 24 hr after operation. Method of measurement: 11 points NRS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactArash Farbood
Shiraz University of Medical Sciences
Outcome results
None listed