The effect of fluoxetine in improving the quality of life in patients with cancer

Comparison of fluoxetine and placebo in improving the quality of life in patients with solid cancers referred to Imam Khomeini Hospital of Ardabil (double blind study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015012220751N1

Enrollment

150

Registered

2015-02-18

Start date

2015-01-30

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer. Malignant neoplasm of stomach

Interventions

Intervention 1: Control group : oral prescription of similar placebo daily for 12 weeks. Intervention 2: Intervention group:oral prescription of fluoxetine capsules 20 mg daily for 12 weeks.

Treatment - Drugs

Control group : oral prescription of similar placebo daily for 12 weeks

Intervention group:oral prescription of fluoxetine capsules 20 mg daily for 12 weeks

Eligibility

Sex/Gender

All

Age

15 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: an age of 15 years or over; a definitive diagnosis of cancer confirmed by a specialist; laps of a minimum of one year from the diagnosis of the cancer; the lack of a known psychological problems ; being a patient with a definitive diagnosis of solid cancer being treated by or prepared for chemotherapy; being out of an acute phase of the disease and within stable clinical conditions; voluntary decision for participation. Exclusion criteria: lack of interest for participation in the study; use of medications with depressive symptoms; presence of other psychiatric diagnoses.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Improving the quality of life. Timepoint: befor and after intervention. Method of measurement: SF-36 questionaire.;General health. Timepoint: before and after intervention. Method of measurement: general health questionaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBehzad Mohammadi

Ardabil University of Medical Sciences

behzad.mohammadi.arums.ac.ir+98 45 3335 3905

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026