Cardiac Surgeries. Cardiac insufficiency Heart failure following cardiac surgery or due to presence of cardiac prosthesis
Conditions
Interventions
Intervention 1: Intervention group: After induction of anesthesia, patents received GIK (40 m eq kcl plus 40 unit Reg ins plus 500 cc DW 10% ) with continuous infusion and the rate of 1 cc / kg / h to
Treatment - Drugs
Placebo
Intervention group: After induction of anesthesia, patents received GIK (40 m eq kcl plus 40 unit Reg ins plus 500 cc DW 10% ) with continuous infusion and the rate of 1 cc / kg / h to 24 h
Control group:patients in the control group received infusion of normal saline after induction of anesthesia.
Sponsors
Vice Chancellor for Research, Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 80-30 years, the first heart surgery, coronary artery bypass graft surgery, the patient informed consent for inclusion; EF less than 40% Exclusion criteria: Pregnancy; lack of informed consent; patients undergoing dialysis; 200 mmol / L ? Cr; acute coronary syndrome; 5- 350 < FBS; In the circumstances that infusion of GIK will be stopped: 5.5 mmol / L <K increased cardiac markers such as troponin and CPK
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the effect of GIK on serum lactate. Timepoint: At 0-24 and 48 hour after surgery. Method of measurement: Blood sample. | — |
Secondary
| Measure | Time frame |
|---|---|
| To determine the effect of GIK on incresing CVO2. Timepoint: At 0-24 and 48 hour after surgery. Method of measurement: ABG of blood sample from central vein. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactEnsieh Shahriari
Shiraz University of Medical Sciences
Outcome results
None listed